ѹҡտ (EPO ) Сͺ¡ôѹӤѭ ôԡ СôŹԡ 繡ôѹ ˹ҷӤѭҧ ǹСͺͧѧҧ, 鹡Դͧ eicosanoid ҧ¢Ҵôѹ繨Դҡõҧ ԭԺⵢͧҧ¼Դ ǧ ѹ˹ѧ ҡ繼ᴧբºdz;Ѻҧ ª Դͷ˹ѧ м˹ѧ駡Ҥ
Atopic dermatitis ҡõ硨繼˭ դ Դ㹡÷ӧҹͧ delta-6 desaturase ö ¹ô linoleic acid GLA ˹ѧ ᴧ բºdz˹Т;Ѻ 繵 ѡɳТͧä Atopic dermatitis
ա֡Ҿ ҡâͧäдբѺзҹ EPO դйѡä Atopic dermatitis ѧ ѡẺ conventional treatment emollient, Mild topical corticosteroid ѡ Դ͡ ҡբ ѧѡ 2 ѻ֧Ѻзҹ EPO 2-4 ᤻ ѹ 2 ˭ 4-6 ᤻ ѹ 2 (EPO բ㹷ͧҴҴ 500 mg. лСͺ g-linolenic acid 40 mg.) ҡèдբ 2-3 ѻ ҧ 8-12 ѻ ҡâҧ§չ оŴӹǹ EPO ŧҷöǺҡ ͧä ա§㹼Ѻзҹ Phenothiazine зԴѡ EPO ʹ˭ԧ駤Т ص
բѧࡵҤѺзҹ EPO 繻Ш оҼ˹ѧ¹º (smoother) ͡ѹ EPO ͡ķ¡Ŵѡʺͧ˹ѧѹͧҨҡ eicosanoid 繵͡ķͧ histamine
äԹ (Psoriasis) ҡբѧࡵҪʡ ä Psoriasis ҨդѹѺáԹ ҷҡ Ѻзҹ ÷ Saturated fatty acid ͡ ä Psoriasis EPO Ѻ駡 ӧҹͧ eicosanoid ÷ ˵ءԴä Psoriasis
͡ҡ 㹡óᾷ Etretinate ѡ Psoriasis EPO ͤǺѹʹ ٧ (hypertriglyceridemia) ҡ Etretinate
ǵǨдѺ linoleic acid ʹ Դ˹ҵ ͧ˹ѧdz٢ (follicular hyperkeratosis) ѹ˵آͧԴѡʺ Ѻзҹ EPO ѡ/ͧѹ ͧҹҹ ҧ 6 ֧繼šѡ (90%)
ҧá 㹰ҹᾷ˹ѧ й EPO 繵㹡ѡäѧ EPO ҧ㹡ѡ (monotherapy)
|
